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These structural troughs are ancient features.
Bidirectional promoters are ancient features, exhibiting orthology from human to Fugu rubripes[ 8].
The high sequence variation and large number of indels between copies of individual elements suggest that MITEs are ancient features of epichloid genomes.
Furthermore, we find that the presence of SM proteins and the tethering complexes is wide spread, suggesting that they are ancient features of the membrane-trafficking machinery.
We identified RGS7 in both chytrid fungi and holozoans (fig. 3 and supplementary fig. S6, Supplementary Material online), and therefore, the ancient duplication of G protein beta and its partner, RGS7, are ancient features of holozoans.
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There are ancient texts.
The woods are ancient.
They are ancient.
The 90s are ancient history.
Presumably, the rocks are ancient.
These proteins therefore seem to be very ancient features that are conserved between oomycetes and vertebrates, and they have been coopted in vertebrate species to cleave the brain APP polypeptide.
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