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The phrase "are a large proportion" is correct and usable in written English.
It can be used when discussing the size or extent of a particular group or category in relation to a whole.
Example: "In the survey, respondents who identified as environmentally conscious are a large proportion of the total participants."
Alternatives: "constitute a significant portion" or "make up a considerable share".
Exact(16)
There are a large proportion of mesopores in the 2 10 nm pore size range.
A lot of staff at Sure Start are women, but so are a large proportion of those using the service as well.
Seventy-seven percent of its galleries are European, as are a large proportion of its collectors, who include the French magnates François Pinault, head of the French retail company PPR and owner of Christie's, and Bernard Arnault, chairman and chief executive of LVMH.
This U-shaped distribution characterizes the nature of pedestrian street-crossing behavior, showing that in general there are a large proportion of pedestrians who cross the street immediately after arriving at the crossing point, and a large proportion of pedestrians who are willing to wait for the entire red-man phase.
This assumption was supported by the fact that although new triptan users are a large proportion of total users, the percentage of triptans users during the years has remained low.
Here there are a large proportion of convenience stores (some 16% of all retail provision), a Co-op supermarket, a Greggs bakery, a Lloyds TSB bank, a Post Office, a Herron frozen food store and several bookmakers.
Similar(44)
For example, many of the lowest-paid occupations, such as bar and restaurant staff, hairdressers, and cashiers, are mainly private sector jobs, while there are a larger proportion of graduate-level and professional occupations in the public sector.
There are encouraging signs that institutional maternal mortality is decreasing, but infectious diseases are a larger proportion of the deaths.
That feels right to me -- and 85percentt is a large proportion of common ideals and purposes.
There's a large proportion of workers of color in unions today.
There is a large proportion of mature students, and many students come from the Buckinghamshire region.
More suggestions(17)
are a large number
are a substantial proportion
are a large percentage
are a significant proportion
are a large part
are a major proportion
are a large share
are a large majority
are a large fraction
support a large proportion
benefit a large proportion
believe a large proportion
present a large proportion
address a large proportion
comprise a large proportion
contribute a large proportion
are a large variety
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com