The Fungal Cytochrome P450 Database (FCPD) archives genes encoding P450s in the genomes of 66 fungal and 4 oomycete species (4,538 in total) and supports analyses of their sequences, chromosomal distribution pattern, and evolutionary histories and relationships.
One major advance involves the construction of comprehensive databases that archive gene sequences and gene expression data.
Many on-line databases that archive gene families allow downloading of all or part of data to user's computer but often do not provide data analysis tools via the database site.
GSMA and similar approaches will be useful for rapidly testing original as well as archived gene expression datasets for specific gene expression enrichment at the group level using either preset gene lists (pathways, promoter elements, disease association, etc) or empirically derived gene expression signatures [ 2].
To identify and archive genes encoding the abovementioned key components, protein domain profiles were determined from reference sequences obtained from UniProtKB/SwissProt.
In support of Tox21, the NTP is evaluating techniques for mining its tissue archives for gene expression response profiles to expand our ability to link chemicals to genes, genes to pathways, and pathways to disease.
We have developed the Repository of Antibiotic resistance Cassettes (RAC) website to provide an archive of gene cassettes that includes alternative gene names from multiple nomenclature systems and allows the community to contribute new cassettes.
A partial match to UCN1 was found in the trace archives although this gene was not found in the pig genome assembly studied and lacks of external validation.
However, a small percentage of windows, especially in the highly repetitive subtelomeric regions containing VSG gene archives, which are critical for antigenic variation in T. brucei (Pays et al. 2004), had high numbers of reads mapped.
It now archives > 8000 genes from seven plant species distributed in 11 UPS-involved gene families.
