Trials were established for three archive samples exhibiting different degrees of yellowing.
The method is tested on a selection of archive samples, and compared with results from high-resolution gamma-spectrometry.
The X-Rite I1 Pro was used in reflectance mode with 3 data points measured and averaged at each location used on the archive samples.
The study and the use of archive samples for the study was approved by the Ethics Committee of the Innsbruck Medical University (study UN 3174).
The study and the use of archive samples for this project were approved by the Research Ethics Committee of Galicia and the Ethics Committee of the University of Santiago de Compostela.
The IRB waived the need for consent for use of the archive samples, and the samples were analyzed anonymously.
One of the advantages of the QPCR method is the ability to archive samples, and if improvements are made to the assay, they will be retested.
Yet, many promising multiplex antigen assays for parasitic infection are still in development and so the study plans to archive samples for future analyses.
Such large-scale studies seem feasible in light of the recent plan for a global sentinel laboratory that could centralize genotype and archive samples collected worldwide (45 ).
Change in Apo B was assessed in a subset of participants at week 26 based on availability of paired baseline and week 26 archive samples.
