Sentence examples for archival status from inspiring English sources

Most genomic studies dealing with FFPE DNA are relatively small in numbers with the archival status of specimens in most cases remaining unknown [ 4, 16].

FISH results for five out of the six agreed with HER2 status from archival tissue and IF on CTCs, with the exception of patient 3, who was HER2+ based on archival tissue and CTC IF assay but FISH negative based on HER2 FISH analysis on the OncoCEE platform.

Though only one of the four patients with HER2+ status in archival tissue had CTCs amenable for FISH in this analysis, HER2 amplification was detected in the majority of CTCs from this patient except in 3 out of 22 CTCs scored that had <4 copies of HER2, None of the 22 WBC scored had >2 copies of HER2.

Mutational status in archival tumour tissue and clinical data was collected for the retrospective analysis from 111 consecutively treated patients receiving at least one cycle of irinotecan monotherapy.

The aim of this study was to determine whether pyrosequencing may be used to determine MGMT promoter methylation status using archival tissue samples from glioblastomas and to investigate the prognostic significance of MGMT promoter methylation in patients treated in the routine clinic with concurrent temozolomide and radiotherapy followed by adjuvant temozolomide.

The role of mutation status in the archival tumour tissue was first investigated in a test cohort and validated in a prospectively collected study.

Though the data showed generally good agreement between HER2 status in CTCs and archival tissue, the specific differences we observed may be due to several biological and/or technical factors and deserve some discussion.

Large studies of receptor status conducted on non-archival tissue are lacking from this region.

Correlative endpoints included molecular subtyping and gene expression studies on pre-treatment archival tissues, and determination of germline BRCA1/2 status.

In patients with unknown HER2 status (n = 33), primary archival tumor tissue was requested from the corresponding Department of Pathology for HER2 assessment.

Archival tissue DNA was interrogated for methylation status using the multi-gene methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) assay.