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Two final cases (#7, 8) had heterozygous BRCA1 methylation in both the archival sample and matched pre-treatment tumor biopsy.
The HST archival sample has an excess of high-stellar-mass, high-SFR inactive galaxies because of the large number of observations of luminous infrared galaxies.
Moreover, its low DNA input requirements and applicability to archival sample collections has the potential to unlock previously inaccessible molecular information from informative cohorts, as demonstrated for HIT-SIOP-PNET4.
By mixing these novel survey data with our initial archival sample (n=3417) and performing repeated cross-validation with subsampling, we created a classification algorithm that performs with AUC=0.89±0.01 using only 15 questions.
Two of the 12 cases with material available for analysis (#1, 2) had homozygous and heterozygous BRCA1 methylation, respectively, in the archival sample, and no evidence of methylation in the pre-treatment tumor biopsy (Table 2), consistent with loss of methylation.
An archival sample of 488 patients seeking surgical treatment for clinical obesity completed a standard battery of pre-operative psychosocial measures.
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Formalin-fixed paraffin-embedded archival samples of 34 AT/RT were retrieved from the archives of the Institute of Neuropathology, Münster.
5 - #90, Folder 1, archival, Samples: paint and fabric samples.
6 - #128, Folder 3, archival, Samples, Catalogues: samples, 1 catalog.
14 - #92, Folder 1, archival, Samples and Specs.: color samples, specifications.
12 - #102, Folder 2, archival, Samples: fabric and carpet samples, business card.
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