Sentence examples for architecture disruption from inspiring English sources

This was associated with a remarkable amelioration of colonic architecture disruption and a significant reduction in pro-inflammatory cytokine production.

As a consequence, organ dysfunction is caused by both organ architecture disruption and the direct cytotoxic effect of amyloidogenic light chains.

Stabilisation of G4 leads to telomere architecture disruption with a consequent detrimental effect on cell proliferation, which makes these agents good candidates for chemotherapeutic purposes.

Loss of gkt during neuronal development leads to a severe CNS architecture disruption that is not dependent on the Crb pathway but probably results from the disrupted localization of other membrane proteins.

This review focuses on how the microbiota drives intestinal disease through alterations in microbial community architecture, disruption of the mucosal barrier, modulation of innate and adaptive immunity, and dysfunction of the enteric nervous system.

It is worth noting that, regardless the number of previous pregnancies, the placentas from recrudescent females typically showed iRBC in the maternal blood spaces, inflammatory infiltrates, erythroblast accumulation in the fetal blood, placenta architecture disruption and trophoblast basal membrane thickening (data not shown).

LBR-induced reorganization of nuclear architecture and disruption of OR aggregates perturbs the singularity of OR transcription and disrupts the targeting specificity of the olfactory neurons.

Lens transparency is critically dependent on the maintenance of an ordered tissue architecture, and disruption of this order leads to light scatter and eventually lens cataract.

An enlarged pelvic node contained circumscribed neoplastic infiltrates in perifollicular and interfollicular areas consisting of large cells arranged in a reticular pattern with nuclear atypia, atypical mitoses, and apoptosis, but without glandular architecture or disruption of overall architecture.

Moreover, in gerbils infected for 9 weeks and 8 months, severe destruction of the normal antral mucosal architecture with disruption of the lamina muscularis mucosae (Figure 4E) was seen in 4 and in all animals, respectively.

Abnormalities in epithelial architecture through disruption of AJs and impaired expression of E-cadherin are implicated in chronic gut inflammation and colorectal cancer (CRC).