Exact(9)
Recent studies point to a crucial role of RNA as an architectural factor for shaping the genome and its nuclear environment.
While RXR can regulate gene expression due to its intrinsic ligand-activated transcription function, this receptor can also regulate transcription by functioning as a ligand-controlled DNA architectural factor.
PRRI contains binding sites for sequence-specific TFs, NF-κB, SRF and Sp1, whereas PRRII encompasses three binding sites for the architectural factor HMGA1 and one for Elf-1, a lymphoid-specific protein that belongs to the ETS TF family.
ChIP analysis was also performed for UBF1, an architectural factor regulating RNA polymerase I transcription.
We hypothesize that control of nucleolar number by CTCF is linked to its global function as an architectural factor, in association with proteins such as B23 and lamin B1.
Thus, CENP-V appears to be an architectural factor that can influence the compaction of heterochromatin in mitosis and its distribution in interphase, rather than adjusting global levels of particular histone modifications per se.
Similar(51)
It is not simple to determine a sustainable memory bandwidth as many complex architectural factors can affect it.
Individual differences in skill acquisition are influenced by several architectural factors.
The airflow pattern on the spectators' terrace in stadia is affected by numerous architectural factors, such as form, size, permeability, i.e. the morphology of the building.
Optimizations of parallel programs for a many-core platform are viewed as a multifaceted problem, where both system and architectural factors should be taken into account.
This study investigated which architectural factors contribute to a sense of home and how these can be implemented in the design guidelines.
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