There's a master of ceremonies (the eager Brian Davis) and a talented cast playing archetypal functions: the Starlet, the Legend, Mr. Soft-Shoe, a chorus line, a male trio.
This observation, combined with the association with more aggressive clinicopathological features and worse survival, led us to hypothesize that, in this context, SOX2 may have other archetypal functions, associated to stemness features.
The resource of 7635 ICPs provided here can immediately focus candidate lists on archetypal chromatin functions and boost our understanding of chromatin-based processes as our biological validation demonstrates.
At this point, it would seem that the archetypal female will function as the enabler of their intimacy with each other, which they dare not act out any other way.
Together with technological advances in the cell-specific manipulation of gene dosage, these observations have now revealed that the function of this archetypal paracrine/autocrine intraglomerular signaling network is critically affected by both subtle changes in isoform balance and subtle fluctuations in the intraglomerular milieu [ 10, 11].
It functions like glutathione, the archetypal redox buffer, which is not produced by mycobacteria (Ref. 71).
Functional studies and detailed characterization of the components of T4SSs diverse from the archetypal T4SSs will enhance our understanding of the function and diversity of bacterial secretion machines.
A clear example of the connection between disordered neutrophil function and CD comes from the archetypal neutrophil defect of chronic granulomatous disease (CGD), in which 40% of patients develop bowel disease indistinguishable from CD (Marks et al., 2009).
Distinguished as archetypal phagocytes, macrophages provide a diverse array of functions during development, homeostasis, tissue-repair, and immunity to pathogens.
Although Arabidopsis γCA1-3 (but not CAL1, CAL2) have retained nearly all residues known to be structurally or functionally important in the archetypal γCA (Cam) from the methanogenic archaeon Methanosarcina thermophila [ 11], including the Zn2+- binding residues H81, H117 and H122 [ 10], the function of γCA homologs in plant mitochondria is still largely unknown.
