Sentence examples for approximation of the GS-alignment from inspiring English sources
As an approximation of the GS-alignment, a 3D-alignment is commonly used not quite reasonably.
In all computations, we use a Currie [31] approximation of the independent alignment tensor from the Doi Edwards reptation theory.
On the other hand, the non-progressive strategy used in MSARC yields a reasonable approximation of the reference alignment (see Figure 7 ab)).
Coverage (in various forms handled in the current scoring functions) is a crude approximation of the (alignment) hypothesis complexity.
Finally, the high concordance between significance of pathway alignment and Jaccard coefficients ≥0.3 (P < 10−) indicates that the Jaccard coefficient is a good approximation of the more elaborate pathway alignment procedure (25).
Obviously, it is important to take into account the "quality" of the obtained alignments, i.e. how closely the algorithms manage to restore the "gold standard" alignment (GS-alignment), which superimposes positions originating from the same position in the common ancestor of the compared sequences.
Thus, if all binding sites in a region are highly conserved, the approximation of a single alignment is adequate and BigFoot may not significantly improve upon traditional methods.
The final size of the physical map of BACs was 303 Mb based on an approximation of the band size of fingerprints, and BES alignment mapped these contigs onto 271 Mb of the 272 Mb genome.
The goal is to provide a lower bound approximation of the real NW score along the whole alignment.
In summary, reformulation of the classical global pairwise alignment paradigm allows for the interpretation of the alignment score as a shortest-path approximation of the kernel score of a pd rational kernel working on biological sequences.
The sum of all scores over alignment columns for a query pair of sequences serves as an approximation of the likelihood ratio statistic comparing the model of independence (null) with the model of homology (alternative).
