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Once-daily MSER approaches maximum morphine concentration more quickly, approximates maximum concentration longer, and demonstrates less fluctuation in morphine concentration during a 24-hour period than CRM dosed twice daily.
We note that MP gives superior performance when evolutionary rate is variable for the set of characters and approximates maximum likelihood (ML) when using large numbers of multistate characters (convergence is less likely with large number of character states) [ 54].
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The Fokker Planck equation allows for approximate maximum likelihood estimation.
The maximum likelihood estimator and the approximate maximum likelihood estimator of R are obtained.
Furthermore, a curve termed approximate maximum sum rate is shown in Figure 4.
It shows that the log-likelihood reaches its approximate maximum after 100 150 iterations.
Moreover, we derive a sequential approximate maximum a posteriori (AMAP) estimator.
An approximate maximum likelihood approach is also possible by numerical differentiation.
The Laplace method, which produces approximate maximum likelihood estimates, was used as a fitting procedure.
The approximate maximum bite force was increased at 3 months after wearing implants (paired t test, p < 0.005).
The GMRf model parameters are adaptively estimated from the observed data using an approximate maximum likelihood (AML) algorithm [12].
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