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As shown in Figure 3, the repeat composition of C14MC approximated the expected situation of the whole genome, (equal amounts of LINE and SINE integrations on the plus and minus strand).
Although the rank order of sites derived from the plasmid standards was reproducible and approximated the expected result, separation between groups was greatly decreased as compared to the analysis based on read number, and distinction of groups was impossible due to overlap (Additional file 1: Figure S3B).
Analysis of the individual sequences revealed that the observed mutagenesis rate closely approximated the expected rate (3.7% versus 3.5% per amino acid position, respectively) with a roughly equal number of transitions and transversions.
We synthesized and purified bivalent HCAbs and observed that the monomeric molecular weights of HCAbs on a reducing gel approximated the expected size (50 kDa) (Fig. 1b).
In most occasions the estimated distribution, although sometimes roughly, approximated the expected distribution (Fig. 3), except for the bimodal case where the peak of developmentally unstable individuals was not detected (Fig. 3 bottom row).
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We derive lower and upper bounds to this highly complex problem by approximating the expected total system costs across the normal and all probabilistic facility disruption scenarios.
A numerical experiment shows that our approach approximates the expected waiting time at the bottleneck with about 8% relative errors while others show 40 80% relative errors.
Moreover, it is demonstrated that the subgrid-scale energy transfer incorporated by the proposed method very well approximates the expected energy transfer as obtained from appropriately filtered direct numerical simulation data.
This panel shows a close agreement between the expected inhibitory shift at time (t+d) obtained from simulations (red curve), and from Eq. (27) (black curve), which approximates the expected inhibition by assuming that during the inhibitory delay all inputs will arrive at regular intervals.
One forward-looking formula used for approximating the expected time before a neutral allele becomes fixed through genetic drift, according to the Wright Fisher model, is : \bar{T}_\text{fixed} = \frac{-4N_e 1-p) \frac{-4N_e 1-phere T is the number of generations, Ne is the effective population size, and p is the initial frequency for the given allele.
At E17.5, the frequency of mgRb Rb−/−:p130−/− double knockout (KO) embryos dropped to 1/59 (1.69%), whereas viable Rb−/− single knockouts were present at 9/59 (24%), approximating the expected 25% frequency.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com