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Further, automated algorithm-based analysis has been found to reasonably approximate manual analysis of microcirculatory video for assessment of the physiological microcirculatory reserve.
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In separate validation work on 30 stroke patients, Quantomo-generated volumes closely approximated manual tracings with high inter-rater reliability (intraclass correlation coefficient = 0.98).
The low correlation between manual assessment and instrumented inferior translation measurements indicates that inferior translation is more difficult to approximate manually.
With a control algorithm designed to better approximate realistic manual control by an occupant, electrochromics achieved significant savings (48%and37%7%, respectively without and with overhang).
The multimodality criterion for splitting is arbitrary, but this is an intuitively reasonable criterion that approximates common manual gating practice, and in practice this criterion successfully isolates biologically significant subpopulations (below).
Manual approximate binary masks were created separately for the heart valves, papillary muscles, and larger trabecular structures (in places where they were sufficiently clearly separated from the endocardial surface) and superimposed on the segmented image stack to numerically tag each separate region with an identifier different to the normal myocardium.
Both splitting and merging use unimodality as the guiding principle for cluster separation, as this is an intuitively reasonable criterion that approximates common practice in manual gating.
By using manual processes, the approximate digitized data could finally be made.
These theories leaded to new methods of design that could approximate the values obtained by manual means (Gimsing and Georgakis 2011).
To verify these results, we analyzed a different data set using manual measurements of approximate BML volume and cartilage changes.
The volumetric measurements of specific BMLs, based on this segmentation approach, have been reported to have a good correlation and agreement with manual measurements of approximate BML volume [ 6].
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