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But he also wrote that nevirapine was still the nationally approved regimen and that the cost of adding AZT was not yet factored into the budget.
If a multiarm placebo-controlled trial contained an arm using an approved regimen and another using an unapproved regimen, we extracted relevant data from the arm using the approved regimen and the placebo arm.
When used for its anti-inflammatory properties the prolonged half-life for mavacoxib supports the approved regimen in which doses are separated by 2 4 weeks.
The approved regimen in the United States for the treatment of AKs is the twice weekly use of imiquimod 5% cream for 16 weeks [ 12].
The approved regimen for treatment-experienced patients with HCV genotype 2 or 3 was based on data from the FUSION 10 and VALENCE 11 studies.
Two sequences are currently standard of care, and approved regimen: TKI (or VEGF inhibitor) followed by everolimus, or TKI (or VEGF inhibitor) followed by axitinib.
Similar(44)
This can also be extrapolated to heterogeneity in responses to chemotherapy, which has been periodically reported in clinical trials or even in approved regimens.
This study assessed real-world effectiveness of two recently approved regimens; paritaprevir/ritonavir/ombitasvir; dasabuvir (3D), and sofosbuvir/ledipasvir (SOF/LDV) in patients with HCV genotype 1.
Even with the currently approved regimens, many patients die or become too ill to receive more than one or two lines of therapy, especially if their diseases had unfavourable prognostic indicators.
Eligible patients were men and women aged ⩾18 years with a confirmed pathologic diagnosis of locally advanced or metastatic breast cancer, pancreatic cancer, colorectal cancer, cholangiocarcinoma, or glioblastoma that was not curable with approved regimens.
Another randomized trial found that ustekinumab administered using the approved regimens improved joint pain visual analogue scale, but the efficacy appeared varying and lacked a dose-response relationship [ 20].
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CEO of Professional Science Editing for Scientists @ prosciediting.com