Diagnoses are generally made by a transvaginal ultrasound accompanied by CA-125 serum testing, which is currently the only FDA approved molecule for monitoring recurrence [ 3].
The best-studied serum marker for ovarian cancer, CA125 (MUC16), has been evaluated extensively for its utility as a marker of ovarian cancer, and is FDA approved for recurrence monitoring.
Following the 5 phases of screening biomarker development proposed by Pepe et al. [2], HE4, the product of the human epididymis gene WFDC2, was developed into a serum assay [3], [4] that is now approved for remission monitoring of ovarian cancer.
The Cellsearch system (Johnson & Johnson, New Brunswick, NJ, USA) is the only CTC technology that has been FDA approved for the monitoring of disease status in PC (Danila et al, 2011).
Instruments suitable and approved for continuous monitoring in this age group give readings on a measure of cerebral oxygenation based on several assumptions that may not hold true in a given infant – and hence displayed values of cerebral oxygenation may not be appropriate in certain individuals.
Despite its widespread use, cancer antigen 125 (CA-125) is only FDA-approved for monitoring recurrence and therapeutic response [9] [11].
A monitor of this design has been approved for hydrogen sulfide monitoring in Minnesota.
A new pain monitor, analgesic nociception index (ANI®), based on heart rate variability, has recently been approved for intraoperative nociception monitoring.
On April 3rd Mr Ma's cabinet partially responded to this demand by approving a bill for monitoring such pacts with China but still did not agree to the idea of enacting it first.
1,5-AG is approved by the Food and Drug Administration for monitoring short-term glycemic control in persons with diabetes and is sometimes used for monitoring postprandial hyperglycemia (8, 9).
