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Over the last few years, numerous therapeutic proteins and peptides have been approved for clinical usage.
Bortezomib, a peptide inhibitor of proteasome, has been approved for clinical usage in pathological settings such as refractory multiple myeloma (Richardson et al., 2005).
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BioImage Suite is not FDA approved for clinical use.
At present, a single integration inhibitor (raltegravir) has been approved for clinical use.
To date, no gene therapy drugs have been approved for clinical use in cardiovascular applications.
No AKR1C3-targeted agent has to date been approved for clinical use.
A number of thiazolidinediones have been approved for clinical use in diabetes.
Pradaxa (dabigatran etexilate, DE) is a new anticoagulant, which has recently been approved for clinical use.
More than 30 monoclonal antibody-based therapies have been approved for clinical use in the past 25 years.
But none have been approved for clinical use in the United States yet.
Encouragingly, small molecule inhibitors of these pathways have shown promise in clinical trials or are approved for clinical use.
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CEO of Professional Science Editing for Scientists @ prosciediting.com