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In some countries in Latin America, non-innovator biologics have been approved by using legislation in place for synthetic copies of brand compounds (that is, without comparative clinical studies with the innovator).
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Infliximab (Remicade®) has been approved by use in patients with immune-mediate inflammatory diseases, such as Crohn's disease, rheumatoid arthritis, and psoriasis.
All protocols used were approved by The Animal Care and use Committee at the University of Toronto and conform to NIH guidelines.
"This has been especially true of the Enbridge system, and of pipelines that are approved by the Corps using Nationwide Permit 12.
However, officials say the baby's death may have been prevented if the powers, long-applicable to alleged Palestinian terrorists, had been approved by for use by politicians against known Jewish extremists sooner.
All animal handling procedures were approved by the use of laboratory animal committee at National Taiwan University, Taipei, Taiwan (IACUC Approval ID: 97 Animal Use document No. 55).
The protocol was approved by Institutional Committee on Animal Care, Use and Research (Approval no. 2011070502) of the Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine.
It followed a route which was set out by the international aviation authorities, approved by Eurocontrol, and used by hundreds of other aircraft.
Almost half the 55 synfuel plants approved by the IRS use its process.
For this study, an active human tissue use protocol approved by the UAMS Institutional Review Board was used.
Experiments were performed under BioSafety Level 3 by using protocols approved by our Institutional Animal Welfare Committee.
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