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Detailed descriptions of these databases including specifics regarding approvals for use of data for this study are enclosed as Additional file 1.
The study protocol was approved by the Icahn School of Medicine at Mount Sinai and Rhode Island Hospital institutional review boards beginning August 29, 2007, and the approvals for use of HRQOL measures were obtained from the relevant copyright holders.
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These devices are already approved or nearing approval for use in the United States, and hence are the most clinically relevant at the present time.
STN DBS received US Food and Drug Administration approval for use in PD in 2002 and GPi DBS received it in 2003.
Prexige is already approved for use in Britain and Novartis hopes for approval for use in the rest of Europe by the end of the year.
The announcement came as the drug, approved two years ago as a treatment for colorectal cancer, received a new approval for use in treating advanced non-small-cell lung cancer.
But the city never sought legislative approval for use of the park.
In a telephone conference call, the F.D.A. gave emergency approval for use of the untested drug.
Brooke relapsed and was eventually put back on the drug, which gained F.D.A. approval for use in children in May 1999.
But because the drugs are new, it will take at least five years to obtain approval for use in patients.
With this decision, Gleevec now has Food and Drug Administration approval for use in any stage of the disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com