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The F.D.A. as a whole is far more focussed on what happens to drugs before they enter the market: for every seven employees who work on drug approval, only one works on post-market safety.
Before Belviq's approval, only one anti-obesity medicine had been approved for long-term use — Roche's Xenical, which reached the market in 1999 and is rarely used because of modest weight loss and unpleasant effects on the digestive system.
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In contrast to the success that has been met in rheumatoid arthritis (RA), where TNF antagonists, CTLA4-Ig and anti-CD20 therapies are significantly better than the placebo comparators in clinical trials, leading to FDA approvals, only one controlled clinical trial in SLE has met its primary outcome measure.
Until the approval of the GM salmon, the FDA has approved only one product, an anticoagulant derived from the milk of transgenic goats.
The company faces a dearth of recently approved drugs, having received approval for only one new drug since 2005.
Bills that now win approval in only one chamber, the Assembly, should do better with Democrats controlling the Senate and the governor's office.
Limited activity against Gram-negative bacteria and issues with mammalian cytotoxicity have resulted in the approval of only one member of this family, novobiocin (2, Figure 1) for the treatment for human infections.
In the Diet session that ended on Wednesday he managed to win approval for only one-and-a-half of the four big initiatives he hoped to pass.As he prepares for this autumn's budget deals, therefore, the prime minister will have to disappoint the finance ministry if he hopes to win the battle with his party.
Seal Of Approval was the only one of those held up to get involved, finishing strongly into third after being last into the straight.The Melbourne Cup has been put forward as a possible target for several of these but it is not necessarily on the agenda for Seismos, according to Mario Baratti, representing Marco Botti, his trainer.
In fact, since the approval of gemcitabine, only one systemic regimen, gemcitabine + erlotinib, has had a statistically significant benefit for survival compared with gemcitabine alone.
Selection of silicone oil viscosity was mostly based on the availability of the oil in the operating room rather than surgeons' choice: throughout the study period, (prior to FDA approval), Labbafinejad Medical Center carried only one silicone viscosity (1000cs or 5000cs) at a given time.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com