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However, drawbacks include concerns regarding toxicity when being applied systemically, and the lack of approval for application by inhalation in the USA for many years.
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There were significantly more non-approvals for applications from PIs within our organization than for applications from PIs from outside our institution (p = 0.014).
The Food and Drug Administration, which is often criticized for its lack of attention to the risks of widespread use of antibiotics, offers recommended, non-binding guidelines for these drugs but has rarely withdrawn approval for their application.
Passage of the bill was critical to United Airlines' effort to emerge from the Chapter 11 bankruptcy protection that it entered in December 2002 after failing to win approval for its application for federal loans.
Although many chelating agents were tested to label radioisotopes more efficiently, DOTA is the most attractive candidate due to its FDA approval for human application.
Recent endeavor in this regard is a nicotine vaccine which is yet to gain approval for routine application.
Obtaining regulatory approval for clinical application of this technology, as through Clinical Laboratory Improvement Amendments certification, is also a barrier that to date only a few laboratories have cleared.
In accordance with Pahang State Land Administration Directive (Arahan Pentadbiran Tanah Negeri) No. 5/1998, approval for new applications, renewal and re-application of TOLs in Cameron Highlands is subject to the Pahang State Authority.
But many have been unable to win approval for their applications.
Hawaii and Tennessee were still awaiting federal approval for their applications the third week of August.
Bone morphogenic protein 2 (BMP2) is a key growth factor for bone regeneration, possessing FDA approval for orthopedic applications.
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