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The large heterogeneous nature of genomes and both current and future availability of increasing amounts of sequences merit the consideration of methodologies that can appropriately handle the amount of diversity present in large scale biological data.
They have merits of appropriately balancing exploring & exploiting and self-adaptively varying population size to reduce redundant computation.
Assume that an evolutionary pipeline has been established, and all methodological aspects have been appropriately considered: does this merit publication?
"In the current environment, any such allegations will necessarily and appropriately draw inquiry from the appropriate regulatory authorities, even where, as here, they are without merit," Mr. Parsons said.
"The merits of these defamation cases are appropriately left for a court.
As such, it merits further assessment, which may be most appropriately carried out by qualitative methods.
One reviewer wrote "I would like to reiterate that I feel the study has significant merit and if these issues are addressed appropriately, this could represent a major contribution to the field.
It therefore seems likely that protection from other filovirus species with mAb cocktails is possible and that cross-protection with appropriately engineered cross-neutralizing cocktails or broadly neutralizing antibodies merits investigation.
Key questions regarding the use of i.v. iron supplementation in the setting of heart failure merit exploration and could readily be answered by appropriately designed clinical trials.
Each of these methods has merit, but in each case a key factor in whether the method appropriately deals with individual pollutants is the extent to which the pollutants are correlated with one another.
As an appropriately described piece of work, it would be an editorial decision as to whether the results merit publication in this journal.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com