Sentence examples for appropriate surrogate for from inspiring English sources
The ΦX174 bacteriophage was selected as the most appropriate surrogate for the blood borne pathogens mentioned because it satisfies all of these criterias.
The implication is that naturally derived DOC may not be an appropriate surrogate for wastewater derived DOC as a matrix for assessing the fate of micropollutants in engineered systems.
These characteristics make them an appropriate surrogate for primary HPC in evaluating the effects of the critical processing steps.
Therefore, cytotoxicity may often be an appropriate surrogate for systemic toxicity.
This is because the cytoreductive effect is considered the most appropriate surrogate for the extension of a vital prognosis.
But variation in neutral markers is not normally an appropriate surrogate for adaptive diversity (McKay and Latta 2002).
Another possibility is that the early morning plasma FFAs are not appropriate surrogates for nocturnal plasma FFA levels.
In order to support RTRT, appropriate surrogates for affected CQAs as a function of quantified in-process parameters and/or material attributes need to be established and included in release specifications (25).
The immediate biosynthetic precursor to a-Chol, a-7-dehydrocholesterol, was also converted to a-Chol and its esters in cells, suggesting that alkynyl sterols are appropriate surrogates for the endogenous lipids in cell studies.
Further research should focus on assessing if these RCTs lead to subsequent trials focusing on patient-important outcomes or if the outcomes used are indeed appropriate surrogates for more patient-important outcomes [ 21].
In the absence of approved biosimilars in the US, the intent here was to use variability in pharmacokinetics and structural complexity of these small-molecule products as appropriate surrogates for the clinical variability and heterogeneity expected with respect to biosimilars and their reference biologics (see online-only appendix for further details on study drug selection).
