The interlayer spacings of silylated graphite oxides became maximal when 1.1 1.5 molecules of bound silyl groups were attached per C8 graphite oxide unit.
Except 2e, the oxygen permeability coefficients (PO2) of membranes of the silyl-disubstituted poly p-phenylenevinylene)s increased as increasing alkyl length of silyl groupoly p-phenylenevinylene: 15.0, 2d: 20.4 barrers).
The silyl groups and ammonium cations were also easily removed through hydrolysis to regenerate the native HA.
Promising antiviral activity may be achieved by introduction of large hydrophobic substituents in the position 6 of adenosine or bulky silyl groups to the position 5′.
p-Bis(bromomethyl benzene with two silyl groups [SiMe2-n-C8H17 [SiMe2-n-C8H17 [SiMe2-n-C8H17iEt3 (1b), SiMe3-n-C8H17, SiMe2-n-C8H17 (1c), SiEt3-n-C8H17, SiMe2-n-C8H177 (1d), SiMe2-n-C8H177, SiMe2-n-C8H177 (1e)] were polymerized by Gilch method to afford SiMe2-n-C18H37tuted poly(p-phenylenevinylene)s (2a–e).
The corresponding monomers having p-dimethyl-t-butylsilyl and p-dimethyl(10-pinanyl)silyl groups in place of p-trimethylsilyl group in 8a also polymerized in a similar way to give high molecular weight polymers (9b, 9c, respectively; Mw>1×106).
If the oligonucleotide contains any 2'-O-protected ribonucleotide residues, the deprotection protocol includes the second step where the 2'-O-protecting silyl groups are removed by treatment with fluoride ion by various methods.
In particular, insights were sought into the reasons why aryl groups at the acetylene termini give rise to bisphospholes, whereas silyl groups promote cumulene-decorated oxaphosphole formation.
Amide (R2N−) and ketimide (R2C N−) (R=alkyl, aryl, or silyl groups) monoanions are two important classes of monodentate nitrogen-donor ligands in coordination and organometallic chemistry.
We were delighted to find that alkyl-, andl-, and silyl-substituted ynamides 3 a– d were all viable substrates, and that a variety of alkenylstannane partners featuring alkyl, aryl, and silyl groups (19 a– d) could be employed, giving a selection of disubstituted bicyclic cyclohexadienes 4 a– g.
