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The selection of the most appropriate regimen based on HER-2 status remains an uncertain strategy.
Data from clinical trials of various dosages of TMP/SMX in the critically ill population are generally lacking, forcing the clinician to prescribe the drug without clear knowledge of the appropriate regimen.
Prospective, high-quality randomized controlled trials investigating empiric antibiotic therapy to determine the effect of appropriate regimen on clinical outcomes are needed to support the implementation of the ATS/IDSA guidelines.
This established an intermittent regimen of capecitabine 1250 mg/m2 twice daily for 14 days followed by a 7-day rest period as the most appropriate regimen for further clinical development.
In sum, by using an appropriate regimen of doxycycline exposure, the R26rtTACreER locus can be used, even with highly recombinogenic target loci, to generate a sparse set of labeled cells at a developmental time point determined by 4HT injection.
The appropriate regimen intensity may vary by disease.
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Radiobiological modeling is used to design appropriate regimens for the IMRT SIB.
Further studies are required to define appropriate regimens for posaconazole use in children.
Only two of the eight participating centres routinely administered appropriate regimens of antibiotics at the appropriate time.
Predicting a patient's response to treatment would allow tailoring of appropriate regimens and a reduction in treatment-induced morbidity.
Problems on treatment compliance and appropriate regimens have certainly played a role in the emergence of M/XDR in China.
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