Sentence examples for appropriate level of expression from inspiring English sources

These observations led us to propose that Eaf and Wnt4 form an effective auto-regulatory feedback loop to maintain an appropriate level of expression (Fig. 9).

Consequently, many transfected cells must be screened to identify those with an appropriate level of expression.

In this report we evaluated the hypothesis that polarization of the RPE monolayer is essential for regulating the appropriate level of expression of trophic growth factors such as VEGF and PEDF, without increasing VEGF levels to those needed to induce pathologic angiogenesis.

We are proposing a novel methodology for obtaining appropriate levels of expression of genes of interest, based on the prediction of the relative strength of selected synthetic promoters combined with an optimized promoter knock-in strategy.

Although to date no Wnt4 mutations have been detected in any tumors [23], the above observations suggest that Wnt4 signaling may contribute to tumor initiation or progression and that the appropriate level of Wnt4 expression protects against cancer, highlighting the potential importance of the EAF-Wnt4 feedback loop.

Spatial regulation of an appropriate level of Dll4 expression is important in the development of a functional vasculature during physiological and pathological angiogenesis (Duarte et al, 2004; Noguera-Troise et al, 2006; Ridgway et al, 2006).

These results demonstrated that LRP6 restrains adipogenesis and suggested that the appropriate level of LRP6 expression is critical for maintaining the balance of adipocyte and osteoblast formation from their common progenitor cells.

When investigating the cooperation of two transgenes in a transgenic mouse, generally two characterized transgenic mouse lines are crossed, but this is a time-consuming method and maintaining an appropriate level of gene expression is difficult.

Early experiments are demonstrating appropriate levels of gene expression, especially enzymes in toxin metabolism.

Appropriate levels of gene expression were detected using antisense riboprobes, whereas hybridization with the riboprobe in the sense direction resulted in a complete lack of stain (Fig.  2).

This is a good example demonstrating the importance of the choice of a proper drug selection system to obtain appropriate levels of transgene expression.