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Current understanding of influenza infection is limited by the lack of an appropriate human model.
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We have also used the most appropriate human cell model, and this is the first time indeed that the transcriptome of M. tuberculosis has been described in human DCs.
The appropriate digital human model, motion measurements, and kinematics and dynamics computations aid in realizing dynamics analysis.
Constructing an appropriate population for the human model is, therefore, of the utmost importance for the prediction of BA-mediated DILI.
Given the spacial, temporal, environmental and epigenetic complexity of gene regulation, it is essential that the appropriate human cell type or model is utilized when trying to draw inferences between risk alleles and enhancer elements.
Defining the targets and off-targets of a range of human CHD mutations and analysing their expressions in appropriate animal and human models will be needed to rigorously test the hypothesis.
Use of animal models and appropriate human biological specimens is encouraged.
What is "appropriate" human direction and control?
In this context, the assessment of an appropriate neutral model of human evolution is required to identify confidently regions of the human genome that have been targeted by natural selection.
Primary human muscle cells provide an appropriate experimental model that has human physiologic relevance.
Of all the animal models evaluated, juvenile swine are considered the most appropriate animal model for human exposure studies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com