Sentence examples for appropriate gene expression from inspiring English sources

Such metabolic optimization is challenged with identifying the right gene targets, and then determining and achieving appropriate gene expression levels.

Gaydos, L. J., Rechtsteiner, A., Egelhofer, T. A., Carroll, C. R. & Strome, S. Antagonism between MES-4 and polycomb repressive complex 2 promotes appropriate gene expression in C. elegans germ cells.

Successful execution of differentiation programs requires cells to assess multitudes of internal and external cues and respond with appropriate gene expression programs.

The present gene transfer system with controllable efficiency and timing would be useful in tissue engineering applications because cell differentiation can be induced effectively by regulating appropriate gene expression with suitable timing.

However, the molecular mechanisms by which SOX10 guides the appropriate gene expression programs necessary to promote the melanocyte lineage are not fully understood.

Alternatively, the need to initiate termination for appropriate gene expression during stress has been demonstrated during oxidative stress in Caulobacter crescentus [18].

The examination of two appropriate genes expression (KCNQ1; KCNH2) at the transcription level by QRT-PCR in a group of LQTS patients and a healthy control group showed different transcriptional activities of KCNH2 gene in LQTS2 patients compared to the control individuals.

We thus hypothesize that transmission of chromatin states from parent germ cells via sperm and oocyte to the nascent germ cells in offspring protects germline-appropriate gene expression patterns in the developing and adult germline.

Thus, cells in Chd4 −/− embryos continue to express multiple lineage markers even at the blastocyst stage, and fail to establish exclusive lineage-appropriate gene expression programmes.

These factors may stabilize lineage-appropriate gene expression patterns during the commitment process (Landeira et al., 2010; Pasini et al., 2007; Schmitz et al., 2011; Wang et al., 2012).

The observation that these embryos are subsequently unable to properly form the TE lineage is consistent with a model in which expression of multiple lineage-specification factors interferes with the ability of a cell to resolve a lineage-appropriate gene expression programme.