The phrase "appropriate efficacy" is correct and usable in written English.
It can be used when discussing the suitability or effectiveness of a method, treatment, or intervention in a specific context.
Example: "The study aimed to evaluate the appropriate efficacy of the new drug in treating chronic pain."
Alternatives: "suitable effectiveness" or "proper efficacy".
Seizure counts remain an appropriate efficacy endpoint; however, ascertainment in infants and younger children may require EEG monitoring.
However, biosimilar monoclonal antibodies provide many challenges compared with first-generation biosimilars, growth factors, and hormones, because they have shown only a modest clinical effect, and are often used in combination with other more toxic therapies, making it difficult to design studies that allow appropriate efficacy and safety assessments compared with the original products.
Understanding the PK and PD of mAbs and their biological and mechanistic underpinnings are crucial in enabling their design and selection, designing appropriate efficacy and toxicity studies, translating PK/PD parameters to humans, and optimizing dose and regimen to maximize success in the clinic.
Finally we might consider whether 2-year outcomes are in fact the most appropriate efficacy outcome.
Periodically review and evaluate the accumulated study data for participant safety, study conduct and progress, and, when appropriate, efficacy.
Finally, passengers pass through arrival screening using the same framework described above, using the appropriate efficacy parameters.
Inclusion of patients with brain metastases early on in the clinical development of a drug or a regimen is needed to generate appropriate CNS efficacy or non-efficacy signals.
The RCP utilizes methods appropriate for efficacy studies, and random assignment is needed to provide answers to clinical questions.
An exploratory analysis suggested that volume change may be a more appropriate primary efficacy endpoint in trials of CNS disease.
In such cases, rather than or before dealing with surrogacy issue, one has to define the most appropriate clinical efficacy endpoint.
We matched the specific types of disease cases with the most appropriate vaccine efficacy estimates, preferably based on clinical trial data gathered in European countries rather than from other continents.
