Sentence examples for appropriate conformation from inspiring English sources

MPER-based peptide should be properly combined with lipids to present an appropriate conformation capable of engaging B cells and inducing neutralizing antibodies.

In recent years, other viral proteins, as a scaffold, or modified HIV-1 Env were used to explore the appropriate conformation of MPER capable of inducing neutralizing antibodies.

In this COX-1 docking study, the designed molecule had not created appropriate conformation inside the active site of COX-1 enzyme due to the bulky amino acid residue Ilu523 and non-polar moieties of the His513.

Analysis by flow cytometry indicated that some 6D9 fragmentsments were unable to construct an appropriate conformation, and that most of the 6D9 fragmentsments displayed on yeast-cell surface exhibited higher binding affinity, stability, and catalytic activity.

The modification of the aryl moiety of the AMAA system has shown not to provide especially good CDAs while the introduction of a sterically hindered tert-BuO group results in a more appropriate conformation leading to 2-naphtyl-tert-butoxyacetic acid (2-NTBA) as the most efficient CDA for thiols.

It follows that the immunogen should contain both MPER and other regions in the gp41 ectodomain with appropriate conformation.

The conformations of the two cyclic salinomycin derivatives were analyzed by ROESY spectrum in DMSO-d6, indicating derivative 7 may adopt more appropriate conformations for the coordinate with alkali metal ion than derivative 5, which has a closer distance between H3 and H25.

After the cells in PBS had been harvested in the absence of protease inhibitors, the pellet was resuspended in PB buffer containing the appropriate conformation-dependent antibody.

To model ECL2, the data of Conner and co-workers was used to select appropriate conformations [4].

Such structural heterogeneity can be utilized for RNAPII interactions via selecting/inducing appropriate conformations for formation of the preinitiation complex (PIC).

HSP70 genes are coded within MHC class III region and their products are involved in the binding and stabilization of nascent peptides for their correct folding to achieve appropriate conformations and in the removal of misfolded and denaturized proteins [ 8– 10].