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In the animal models for such conditions, embryonic stem cells are harvested and injected into appropriate brain regions, where they are supposed to differentiate into the "correct" neurons.
So, for example, the preternatural ability that footballers have to anticipate the motion of a ball in flight is attained by the overdevelopment of the appropriate brain structure at the expense of the adverb department just next door.
Recently, there is some skepticism regarding the extent to which axon guidance is regulated by molecular gradients in vivo, suggesting that chemotaxis is just one component of a set of mechanisms to produce appropriate brain wiring47,48,49.
Using gamma-band electroencephalography (EEG), a putative marker of cortical disinhibition, to ensure appropriate brain penetration and dose alignment between ketamine and lanicemine, we tested the ability of lanicemine to produce antidepressant efficacy with minimal psychological and physiological side effects.
When your brain encounters sensory stimuli, such as the scent of your morning coffee or the sound of a honking car, that input gets shuttled to the appropriate brain region for analysis.
Genetics of neuropsychiatric disorders, particularly autism spectrum disorders, have pinpointed contactin-4, -5, and -6 (CNTN4, -5, and -6) as potential disease genes in neurodevelopmental disorders and suggested that they participate in pathways important for appropriate brain development.
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Fonov, V. S., Evans, A. C., McKinstry, R. C., Almli, C. R. & Collins, D. L. Unbiased nonlinear average age-appropriate brain templates from birth to adulthood.
Consequently, during sensitive developmental periods, GABAA receptors may act as broadcasters of sexually differentiating signals, promoting gender-appropriate brain development.
Overall, these findings suggest that developmental improvements in behavioral control are supported by improvements in effectively presetting goal-appropriate brain systems.
It is important therefore to study separately the effects of these factors not only on the course of epilepsy but also design new treatments that may not necessarily disturb the gender-appropriate brain development.
We evaluated the impact of using nationality-appropriate brain templates on segmentation by doing tissue segmentation for Chinese participants using Chinese or U.S. child templates for priors.
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