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The phrase "appropriate application of knowledge" is correct and usable in written English.
It can be used in contexts where one discusses the effective or suitable use of knowledge in various situations, such as education, professional practice, or problem-solving.
Example: "The appropriate application of knowledge is essential for successful project management and achieving desired outcomes."
Alternatives: "suitable use of knowledge" or "effective utilization of knowledge."
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Encouragement of appropriate application of clinical knowledge can foster a deep approach to learning and enhance performance on clinical assessments (Norton 2004).
Education, including implementation of carefully developed high-quality guidelines such as the current ABC International Consensus Guidelines, allows the appropriate application of current knowledge to patient care, which will substantially improve the long-term outcomes of current ABC patients worldwide.
Identification of genes with switch-like properties will facilitate discovery of regulatory mechanisms that underlie these properties, and will provide knowledge for the appropriate application of Boolean networks in gene regulatory models.
One especially appropriate application of this technology is vaccination.
But careful planning is necessary not only for the appropriate application of this money.
It develops the appropriate application of radioactive substances and stable nuclides in the field of medicine.
Appropriate application of nitrogen fertilizer aroused people's concern.
This is an indicator for the appropriate application of guidelines.
Articles were scrutinised by two experienced qualitative researchers (MM, ML) and were included in the review if they were based on the appropriate application of established qualitative methods –that data collection, analysis and sample selection were appropriate to the explicit or implicit research question(s) - and contributed to knowledge in the field.
The growing need for fire safety engineering (FSE) design around the world has led to higher education degrees, many of which lack strong foundations in fundamental knowledge and are somewhat deficient in developing skills (application of knowledge) and appropriate attitudes (reflective assessment and synthesis of knowledge).
Wisdom is the fitting application of knowledge.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com