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The MRI acquisition parameters required for post-mortem scanning and changes to MRI tissue parameters with death and fixation made more automated approaches unreliable.
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While calibrating the stiffness properties of the beams to produce acceptable results under gravity loads appeared feasible, the task of recalibrating the models for each successive column removal makes this approach unreliable and unfeasible.
However the lack of current kinetics of N257A CLC-Ka (Fig. 9A left and middle) only allowed us to resolve a restricted range of a putative parabola in the variance mean plot rendering this approach unreliable (not shown).
Indeed, except for two images where a partial occlusion of the background target-object made the results of this computational approach unreliable, the normalized depth-value of the foreground target was always larger than that of the background target in the same image.
The intricacy and nonlinearity of the underlying phenomena makes the above approaches somewhat unreliable for estimating liquefaction-induced lateral spreads.
Recent benchmarking studies confirmed that transcription factor binding sites (TFBS) prediction based on statistical motif discovery approaches is unreliable and thus remains a major bottleneck in the study of transcriptional regulatory regions [1], [2].
The lack of overlap (three genes) between the 70-gene signature of the Amsterdam group (cDNA arrays) [ 7, 8] and the 76-gene signature of the Rotterdam group (Affymetrix oligonucleotide arrays) [ 9] has been claimed as evidence that genomic approaches are unreliable.
An error propagation analysis shows that the first approach is unreliable and that the second approach is the best option.
But this approach is unreliable.
Acquired data suggests that BCI-based approach is unreliable in assessing motor imagery due to its high dependence on subject's innate EEG features (e.g. resting mu-rhythm amplitude).
Previous studies suggest that this approach is unreliable [ 21, 22].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com