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An additional hope is both to gain our ability to identify and understand the specific causes, modifiers, and consequences of disease and to develop approaches to reverse engineer these in such a way as to recognize best treatments and preventions.
The new drug delivery system (DDS) provides promising approaches to reverse MDR, for which the poor cellular uptake and insufficient intracellular drug release remain rate-limiting steps for reaching the drug concentration level within the therapeutic window.
Thus, novel approaches to reverse hormone therapy resistance are needed.
Moreover, there is an urgent need to find novel approaches to reverse MDR in GC.
"Existing prevention strategies have had limited success, so we have to look for creative new approaches to reverse the HIV/AIDS epidemic.
Small-molecule inhibitors of HDACs and LSD1/LSD2 suppress Snail-1-induced EMT and may point the way toward pharmacological approaches to reverse EMT in cancer.
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The finance ministry said Moody's downgrade vindicated the government's recent policy initiatives since "a robust program of macroeconomic adjustment constitutes the only possible approach to reverse the tide and recover credibility".
An approach to reverse this situation might be the development of uneven-aged silviculture, combining biodiversity conservation and timber production.
Lungu [95] presents an approach to reverse engineering of ecosystems of software repositories, that touches on collaboration among developers.
"Organizations are losing the battle against cyberattacks, and the industry is in need of an effective approach to reverse the asymmetric advantage favoring hackers," Polak said.
The basic phases of our approach to reverse engineering are summarised, and related computational difficulties are analysed.
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CEO of Professional Science Editing for Scientists @ prosciediting.com