While pluripotent stem cells hold good future promise to this end, more immediate translation is expected to come from approaches that generate functional VSMCs from adult sources of multipotent adipose-derived and bone marrow-derived mesenchymal stromal cells (ASCs and BMSCs).
Biologically-grounded drug developers (and ultimately physicians) are likely to struggle to gain comfort around approaches that generate or rely upon mechanistically opaque classifiers.
The ability to constantly grow by evolving the service delivery approaches that generate stable revenue is important.
An advantage of knock-in alleles over other transgenic approaches that generate alleles by random integration into the mouse genome is that the precise location of the knock-in allele is known.
By contrast, approaches that generate artificial variation in a non-targeted fashion, for instance by means of evolutionary engineering or mutagenesis, have proven more successful to improve this complex phenotype [ 7].
In line with the study design, data analysis adopted a psycho-social approach that generated four themes and 10 sub-themes which, characterised participants' experiences.
To take this into account, the statistical significance of the trends and correlations were assessed using a Monte-Carlo approach that generated 10,000 synthetic time series that share the same spectral characteristic as that of the underlying time series, thereby capturing any temporal autocorrelation39,40.
Since 2007, several groups in Mali have carried out SRI evaluation and expansion through a more programmatic approach that generated average yields of 7.5 to 9 t/ha, equivalent to more than 50% increase with peaks of 12 t/ha (see photo from Bagadadji, Timbuktu, Mali, at left).
With the goal of reproducing the bench-to-bedside approach that generated alglucosidase alfa and now offers hope for patients with Pompe disease, the Chens made a gift to the Department of Pediatrics to establish the Alice and YT Chen Pediatric Genetics and Genomics Research Center.
With the goal of reproducing the bench-to-bedside approach that generated Myozyme and now offers hope for patients with Pompe disease, the Chens made a gift to the Department of Pediatrics to establish the Alice and YT Chen Pediatric Genetics and Genomics Research Center.
However, for the leopard cat a higher differentiation between groups was obtained using the biogeographic approach that generated a FST of 0.86 (P<0.05) as compared to a FST of 0.32 (P<0.05) for the taxonomic categorization (Table 3).
