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This can be overcome by whole genome association studies and other approaches that capture effects of most QTL that contribute to the population-wide variation in a trait such as genomic selection.
Therefore, the science of carcinogen testing and evaluation must be increasingly multidisciplinary, examining biologic responses from the molecular to the organism, and using test systems and approaches that capture multiple mechanisms and end points.
The approaches that capture inconsistency by a single extra variance component in a mixed effects model [ 8, 9] only aim at quantifying inconsistency and at providing conservative confidence intervals.
We suggest that if such correction yields no or little effect on point estimates and their precision, it need not be incorporated in the bootstrapping approaches that capture the sampling error of the sampling weight estimates.
Other approaches that capture the behavior of all voxels in one summary outcome, for instance by tracking the location of a cluster's "center of mass" as a function of frequency, have as a drawback that they have difficulty dealing with multiple tonotopic progressions simultaneously, especially when oppositely directed.
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In this work we present a defect-based modeling approach that captures the dynamic effects of both oxide-trapped charge and interface traps through calculations of surface potential.
We describe and illustrate the five properties, explain how particular member configurations exacerbate or diminish turnover's effects, and present a new measurement approach that captures these characteristics in a collective context and over time.
This study adopts a configurational approach that captures possible variables (strategy, structure, leadership and decision-making styles) and their relationships with management accounting systems (MAS) from an organizational life-cycle perspective.
To cope with the diversity and complexity of molecular self-assembled nanofibrils, we have developed a mechanical approach that captures membrane dynamicity to suppress cancer cell migration and invasion.
Researchers at MIT are seeking new ingredients in cement that are less energy intensive, while companies such as Montreal's CO2 Solution have an enzymatic approach that captures carbon-dioxide emissions from cement-factory flue stacks, converts the greenhouse gas into limestone, and feeds it back into the cement-making process.
In previous work, we proposed a multi metamodelling approach that captures the complexity of these systems by using a metamodelling hierarchy, built from individually defined metamodels, each capturing different aspects of a healthcare domain, namely, user access modelling, health process modelling, process monitoring, user interface modelling and modelling of the data sources.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com