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When assessing the clinical significance of a detected variant, several approaches of further analysis are recommended to classify variants as deleterious, suspected deleterious, of unknown (uncertain) clinical significance or polymorphic/neutral [ 12].
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Practically any conception of the common good, libertarian or communitarian or anywhere in between, would produce better policy than a factionally-driven approach of further subsidizing the rich while cutting programs for the poor.
However, when implementing a selective screening procedure, it needs to be followed by a structured approach of further clinical diagnostic procedures and evidence-based treatment, as recommended in clinical guidelines [ 6].
To demonstrate the use of these approaches to further understanding of DNA-protein interactions in living cells, we chose to study the CREB transcription factor [ 22- 25].
The study of tumor immunology has led to the development of approaches to further stimulate antitumor immunity.
Participants noted the use of specific biological knowledge to adjust the slope of the dose response estimate as a variant of this approach worthy of further exploration.
56– 59, 63 These studies suggest that autophagy inhibition may be an effective approach worthy of further investigation with broad applications in cancer therapy.
Design approaches for further enhancement of ultrahigh temperature properties of oxide/non-oxide composites are discussed.
A subset of these genes was further studied by using a combination of complementary approaches to further understand IGF-I actions in the inner ear.
Some potential approaches to further investigation of the relationship between asthma and ozone, including those that would link controlled human exposures to population-based studies, are considered.
In addition to recent advances, limitations of current approaches and areas of further research are discussed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com