The phrase "approaches in cell" is not correct and lacks clarity in written English.
It may be intended to refer to methods or techniques used within a cellular context, but it needs additional context to be usable.
Example: "The study explores various approaches in cell biology to enhance our understanding of cellular processes."
Alternatives: "methods in cell" or "techniques in cellular".
Using transgenic and antisense approaches in cell lines, these pathway alterations should then be induced and the predicted development into a DD cellular phenotype tested.
The strongest causal evidence is obtained with transgenic approaches, in cell culture or animal models, to identify phenotypes triggered by such variations [ 21, 22].
Downmodulation of CD146 expression by siRNA or shRNA approaches in cell lines that spontaneously express a high level of CD146 mostly resulted in a decreased migration in three distinct assays, at least one of which involves heterotypic cell cell interactions.
Thanks to their relatively easy isolation from bone marrow (BM) and to their extensive capacity for in vitro expansion, MSCs have been considered for approaches in cell therapy and tissue engineering [ 17– 17].
Therefore our results may lead to novel approaches in cell seeding to develop vascularized bone tissue engineered scaffolds, such as selective, prioritized, or time dependent seeding of different cell types.
Genetic and pharmacologic approaches in cell culture and in vivo allowed us to conclude that maintenance of a proper RARαβ/γ balance is crucial for preserving normal epithelial cell homeostasis.
It describes a wide range of approaches in cell-based drug delivery and highlights exceptional examples.
Therefore, the efficient magnetic labeling of targeted cells offers promising new approaches in cell-based therapy with great potential for cancer treatment [20].
Gain- and loss-of-function approaches in cell-based in vitro systems have been useful in uncovering important roles for lncRNAs, such as modulating chromatin states, maintaining cellular identity (i.e. pluripotency) and regulating cell cycle and translation (Tsai et al., 2010; Guttman et al., 2011; Wang et al., 2011; Yoon et al., 2012).
During the last 10 years, different approaches in cells, mice and non-mammalian organisms have been pursued to obtain such models.
The concept of statistical experimental design and multivariate evaluation was shown to be a useful approach in cell toxicity screening studies.
