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This study aimed to compare different approaches for interrogating text fields for identifying work-related injuries presenting at EDs in Queensland to inform future surveillance of work-related injury using narrative text.
As such, the findings from this study are relevant to other similar surveillance systems in terms of approaches for interrogating text data, with similar issues regarding the use of text data identified by researchers using these other systems [ 10].
Furthermore, the approaches for interrogating text data (even scant descriptions) have applicability across systems regardless of the comprehensiveness of the text, though more detailed descriptions would certainly enable more complete ascertainment of cases.
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Herein, we demonstrate a robust approach for interrogating the role of PRDX1 as a putative protein biomarker in breast cancer.
The three main approaches which have been used for interrogating text data can be summarised as being: Manual review and coding, text search methods, and automated or semi-automated methods employing statistical and/or lexical software tools using Bayesian clustering principles.
This approach has proven extremely useful for interrogating biochemical targets in the complex environment of the cell.
This approach suggests a potentially broad method for interrogating enzyme family members, both known and unknown, in cells and proteomic fractions without the need for individual assay development and isolation.
Overall, ReCLIP offers a potentially powerful alternative to previously described affinity-purification approaches and appears to be particularly suitable for interrogating labile protein complexes.
Single-cell proteomics provides the most direct approach for elucidating signaling network structure and coordination, and for interrogating how that coordination is disrupted by drugs.
This study compared methods for interrogating text fields for identifying work-related injuries presenting at emergency departments to inform approaches to surveillance of work-related injury.
Unfortunately, these approaches tend to be expensive and difficult for most labs to execute, and their resolution often prohibits their use for interrogating GWAS loci.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com