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Transient expression assay using protoplasts, together with biochemical approaches, enabled us to show that CAN1 and CAN2 exhibit calcium dependent deoxyribonuclease activities similar to that of the bacterial SNases.
Nevertheless, using any of 3 different statistical approaches enabled us to identify gene sets differentiating the two populations.
In this case the integration of these multi-disciplinary approaches enabled us to achieve up to a 6 fold greater yield using concentrations an order of magnitude higher than in previous preparative scale batch bioconversions carried out sequentially.
Bioinformatic approaches enabled us to extract six candidate miRNAs.
Molecular biology approaches enabled us to identify the cause of an acute disease and to detect its bacterial origin.
The combination of CE MS-based metabolomiCE MS-basede genometabolomicstomics androaches enabled us to determine chemical changes and understand howholey relate to an observed phenotype.
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Indeed, the multiscale approaches enable us to determine the elastic properties of materials.
These approaches enable us to identify receptors that receive specific information whether or not their respective ligands are known.
Use of different computational approaches enables us to reliably recognize distant relationships, especially when they converge to a common assignment because the methods are often complementary.
This approach enabled us to compare simulated gene expression configurations when using GRNs that differed from those reported before.
This comprehensive approach enabled us to evaluate FRET levels in a single cell using three methods: sensitized emission, standard acceptor photobleaching, and sequential acceptor photobleaching.
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