Sentence examples for approaches chip from inspiring English sources

The results obtained from biochemical approaches (ChIP) are obtained from millions of cells and, thus, are averaged responses that are sometimes in contrast to single cell studies, which show nuclear receptors and other transcription factors rapidly exchange with a promoter array at a much faster rate (seconds [19], [25], [37] [40]).

However recent genomic approaches (ChIP-seq and DHS-seq) show that a large fraction of receptor binding events occur at pre-accessible chromatin.

The two approaches, ChIP-seq and ChIP-chip, yield strongly overlapping results revealing that HLH-1 preferentially binds to promoter regions of genes enriched for E-box sequences (CANNTG), known binding sites for this well-studied class of transcription factors.

In addition, gene knockdown, chromatin immunoprecipitation and sequencing approaches (ChIP-seq) have each identified genes that can be regulated by both HIF-1 and HIF-2, or that are preferentially regulated by either HIF-1 or HIF-2.

Costantino Rocca had just sunk a putt from 65 feet - moments after duffing his approach chip into the 'Valley of Sin' on the 18th at St Andrews - to force a play-off with John Daly.

After punching out into the fairway, Woods overshot the green badly with his approach, chipped to 10 feet and missed the putt.

Compared with the ChIP-on-chip hybridization approach, ChIP-SAGE increases the coverage and resolution to the entire genome [ 28].

In this article, we demonstrate that this is indeed the case by proposing and evaluating a new approach, ChIP-PED.

These H3K27me3 data sets differ in their experimental approach (ChIP-seq and ChIP-chip) and analyzed tissues (supplementary fig. S1 A and data set S1, Supplementary Material online).

Using a genome-wide chromatin-immunoprecipitation sequencing approach (ChIP-Seq), we recently identified binding regions for REV across the Arabidopsis genome (Brandt et al., 2012).

Results: We propose to enrich this existing data analysis paradigm by developing a novel approach, ChIP-PED, which superimposes ChIPx data on large amounts of publicly available human and mouse gene expression data containing a diverse collection of cell types, tissues and disease conditions to discover new biological contexts with potential TF regulatory activities.