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To facilitate the discovery of novel HDAC8 inhibitors, pharmacophore models were generated using ligand and receptor based approaches and validated with a database of active and inactive compounds.
A comparison between the responses predicted by proposed DA method and the BPNN showed a fair amount of the agreement between the two approaches and validated the proposed model and proved outstanding tool for identification of spalled/damaged bearing components.
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The depth at which the current intrudes into the ambient also reveals a good agreement between the two approaches and validates the ability of numerical simulations to reproduce the dynamical features of turbidity currents moving into a stratified ambient.
The new designed burner focusing on the flowing and mixing processes of town gas ejector were optimized by CFD approach and validated by experiment.
The unknown model parameters have been calibrated by means of the non-linear least squares identification approach and validated against real data.
A closed form expression for statistical distributions of fiber lifetimes was established, and was found to compare fairly well with the experimental results, which assessed the approach and validated new findings.
We took the first approach and validated the FFAT-like motifs in ASNA1, RAB3GAP1 and WDR44, proteins that we identified in VAPB immunoprecipitates by mass spectrometry.
In order to simulate non-linear biological complexities, we have previously developed an Enzyme-Centric mechanistic modeling approach and validated it using metabolic network in E. coli.
We therefore took a very clinical approach and validated the position of the tip of the catheter within the integrated CT image against our judgement on catheter tip position derived from fluoroscopy, local electrogram, and tactile information.
Therefore, we took a pragmatic approach and validated the methods that have been used in practice in recent research literature to identify suicides and self-harm outcomes in the CPRD 7, 31, 32.
The approach described and validated here for the meningococcus is one way of achieving this, which employs generic, freely accessible and widely used tools.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com