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They combine theoretical and methodological approaches and primary materials from the natural sciences, and the social sciences/humanities (Brádzil et al. 2006; Mauelshagen 2014, p. 2).
The discordant results reported here between the effects of miR-16 overexpression in an orthotopic transplant model in immunocompromised mice and miR-16 deletion in a primary tumor model in immunocompetent mice demonstrate the importance of utilizing complementary gain-of-function and loss-of-function approaches and primary tumor model systems for the study of metastasis.
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From both ex-ante approach and primary hydrochemical data it can be inferred that springs need to be restored in terms of both quantity and quality.
A minimally invasive approach and primary dural closure associated with good neuroanesthesia along with excellent preoperative postoperative care should be, in our opinion, the preferred way to manage elderly patients with spinal meningioma.
The strength of the PC Monitor is that it builds on well-known frameworks for health care system analysis (such as the structure-process-outcome approach) and primary care research [ 8, 19].
Details of experimental approaches and representative primary data, protein sequence alignments, discussions of the rationale for the kinetics methodology chosen, and calculations of free energy additivities.
Details of experimental approaches and representative primary data, protein sequence alignments, discussions of the rationale for the kinetics methodology chosen, and calculations of free energy additivities may be found in the associated Supporting Information.
This is especially the case among paediatricians, the doctors whom many teenagers approach first, and primary-care providers, who look after women in public clinics.Some states are promoting IUDs more vigorously than others.
The inner loop controller is designed based on IMC approach and the primary setpoint filter is based on optimal performance index.
Two authors (SPT, JK) are clinical investigators for and consultants to Genentech, Inc. RS developed the analytical approach and had primary responsibility for interpreting results and preparing the manuscript.
In fact, the novelty of the MCMC-Mallows approach, and the primary contribution of this work, lies in its flexibility to model arbitrary single, multiple, and partial knock-out designs.
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