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It was shown, for all polymer architectures under consideration, that at a certain temperature and for a certain size of the slit the chains were adsorbed at one of the confining surfaces and after a certain period of time they detached from this surface and approached the opposite one.
Specifically, as illustrated in Figure 7A, in STXK2A, the K259/K263/K264 group of residues interacts with PIP2 lipids that have been sequestered from the N-terminus-facing side of the linker region, and K255/R262 bind to a single PIP2 lipid that approached the opposite face of the STX juxtamembrane helix.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com