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That approach will underestimate failure rates from a patient intolerance standpoint, and thus the approach used in this study is more applicable to situations where endoscopic placement is not available.
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Moreover, it is probably safe to assume that each of these approaches will underestimate the actual rate of error, and may identify entirely separate cohorts of errors.
This approach will likely underestimate the magnitude of the true effect.
bIt should be noted that condom use outside the trial setting is lower and our approach will therefore underestimate the impact of microbicides on HIV incidence.
This suggests that using the standard 3 6 MET absolute intensity approach (1952 5724 counts · min-1) will underestimate PA intensity particularly for older (>60 yrs) age groups, while overestimating PA intensity in younger age groups.
We note that the PA approach to calculating CCS for model structures will underestimate the actual CCS of the structure, as scattering angle is not taken into account during the calculation.
In short, a JEM based approach will yield underestimated associations if the exposure causes the diseases we study.
I would tend to think that they will underestimate.
Liverpool, though, will underestimate them at their peril.
People will underestimate the amount of work they are doing".
"It will underestimate the mortality rate," he said.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com