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We report here an NMR-based fragment screening approach which identified several hits that bind to the C-terminal region of ZipA.
Hybridization probes were designed on the basis of the most variable window approach, which identified species-specific nucleotide polymorphisms in a region of generally high sequence similarity.
Surflex-PSIM was also used as a part of a combined computational approach which identified known PPARα agonists as also being cyclooxygenase (COX) inhibitors [35].
These strategies included linking isolates and a Blast-based approach, which identified contigs with hits to the H. pylori strain 26695 genome.
The studies were carried out with a participatory approach which identified the importance of the local pigs and feed resources and the enthusiastic adoption of the biodigester technology and the production of duckweed based on the fertilized ponds.
These findings contrast with those of a targeted next generation sequencing approach, which identified the cause in 18% of patients in a similar study cohort (Nemeth et al., 2013).
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The new adaptation retains Mr. Armstrong's folk-fable approach, which identifies the characters by their roles -- Father, Mother, Boy, Teacher.
This componential approach, which identifies certain affective, cognitive and psychomotor elements as primary facets of the disorder may require the systematic combining of clinical rating, self-report and objective performance measures.
Alternatively, marker-assisted breeding (MAB) is a more efficient approach, which identifies the usefulness of thousands of genomic regions of a crop under stress conditions, which was, in reality, previously not possible.
"We now have an evidence-based approach which identifies patient need and matches our response accordingly.
This problem can be solved by a biometrics approach, which identifies an individual based on his/her characteristic traits.
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CEO of Professional Science Editing for Scientists @ prosciediting.com