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All benchmarks used for validating the MedSim approach were compiled in such a way that every candidate list contains exactly one true positive.
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The evaluation is based on two data collection approaches, which were compiled for the same trips: The first, In Vehicle Data Recorders (IVDR), which were installed in the young drivers' vehicles for a study period of 8 months.
Data were compiled using a qualitative approach.
Arrays were normalized using quartile normalization, and expression estimates were compiled using GC-RMA applying the empirical Bayes approach [58].
Through a rigorous statistical approach, data from several independent L. infantum and L. major DNA microarray experiments were compiled and compared here.
As a complementary approach to validate our predicted small molecule targets, we analyzed available high-throughput drug screening data that were compiled in CancerDR [ 67].
Groups of orthologous and close paralogous proteins were compiled with the Sybil comparative analysis package [ 10], which applies a modified reciprocal best-hit approach comprising two clustering cycles.
Outcome measures were compiled and compared.
The programs were compiled with Matlab R2010b.
Then, 2 lists were compiled as follows.
Figures were compiled in Adobe Photoshop software.
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