Sentence examples for approach we subsequently from inspiring English sources

In a stepwise approach we subsequently tested the impact of N-terminal extensions and systematic single amino acid substitutions within the core of this peptide which revealed that an N-terminal extension with the tripeptide sequence ADA increased binding affinity 5- to 6-fold.

Similar to the RFE approach, we subsequently selected the voxel set with the peak classification accuracy for further analysis.

To validate our systems approach, we subsequently verified a novel G1/S and known G2/M cell-cycle block and increased apoptosis as predicted from our enrichment analysis.

Building on this "endophenotype" discovery approach we subsequently found transthyretin (TTR) and apolipoprotein A1 (ApoA1) to be associated with faster declining AD subjects and increased plasma apolipoprotein E (ApoE) levels related to increased Aβ burden in the brain [8,9].

Using an affinity chromatography approach, we identified and subsequently validated that ICG-001 binds specifically and with high affinity (approximately 1 nM) to the coactivator CBP, but, importantly, not to its closely related homolog p300, despite the fact that these two coactivators are up to 93% identical, with even higher homology, at the amino acid level.

We subsequently considered whether our approach would be reliable in the analysis of complex samples such as those that are likely to be encountered in a laboratory.

We selected polymorphisms in these genes based on a hypothesis-free approach, and subsequently tested the most promising ones in a candidate gene analysis.

The language echoes his condemnation of "predatory" capitalism in a speech last year to his party conference, an approach was subsequently adopted approach by coalition figures and which has been regarded in some quarters as one of his more successful attempts to carve out a distinctive policy niche, along with a pledge to stand up for the "squeezed middle".

At HHO the approach was subsequently very different and somewhat revolutionary.

This approach was subsequently validated using standard compounds and liver tissues.

A robust regression approach is subsequently developed to address the impact of contextual variables on efficiency levels.