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The main issues are poor designs of the systems, as many had been modified after a previous approach was unsuitable; and their poor management, due mainly to an absence of skilled people taking responsibility for water quality and mechanical problems.
However in this rural and remote setting, with high basic medical needs and limited resources, it was considered that a vertical approach was unsuitable.
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However, in the context of conditionally replicating Ad vectors (CRAds), this approach is unsuitable since the targeting moiety is lost following the initial infection.
Collectively, this set of data suggested that the MLTC approach is unsuitable to efficiently induce CTLs specific for the autologous tumor from PBMCs in the NSCLC setting.
However, this approach is unsuitable for characterizing and comparing cities because it ignores the fundamental emergent phenomenon of agglomeration [6] [11] resulting from non-linear interactions in social dynamics [6], [7], [10] and organization [11], [12] as cities grow.
Therefore, this approach is unsuitable for routine clinical application, and several attempts have been made to sort out these difficulties.
Although in extensive use, the syndromic approach is unsuitable for diagnosing cervical infections in antenatal care attendees in Botswana.
Hence, a standardised approach is unsuitable and local circumstances must be taken into account when planning guideline implementation.
Are fishes and the ecosystems they inhabit so different from other species and ecosystems that a universal approach is unsuitable and inapplicable?
Remaining long-range distributions in some Pontohedyle species might indicate that the dispersal abilities of meiofaunal slugs are currently underestimated, or that our approach is unsuitable of detecting an even higher degree of cryptic radiation in recent times.
Whereas RT PCR interrogation of archival FFPET has proven to be a reliable tool and is widely used (Cronin et al, 2004), this approach is unsuitable for large scale discovery-based investigation owing to the limited number of genes that can be assayed in one experiment.
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