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After checking the convergence of the present approach, validation is carried out by comparing numerical results with the available results in open literature.
Using the accuracy profile approach, validation results gave a LOD and LOQ for dicentrine of 3 μg/ml and 10 μg/ml, respectively.
The approach validation is done on voiced parts of the Keele University database by calculating the absolute and relative errors between the OQ estimated from the speech and the corresponding EGG signals.
Using this approach, validation is a process that involves accumulating evidence to provide a strong scientific basis for proposed score interpretations.
As for the approach validation, it outperformed univariate approaches in bundle discrimination at different maturational stages, and its discrimination capacity was extremely high.
According to this approach validation of the extraction procedure for different sample matrixes is necessary and is done by assessing the ability of the extraction method to provide suitable DNA from the specific matrix.
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In conclusion, our study provides novel information with rigorous bioinformatic approaches, validation and replication data about genes and pathways that might be responsible for perihematomal secondary injury but also of endogenous repair mechanisms becoming targets of therapeutic interest.
We call this approach visual validation.
In order to use the proposed computational approach, a validation against experiments is needed.
This paper presents the analytical formulation of the proposed approach, whose validation follows in part II.
Fig. 1 Four inferences in Kane's argument-based approach to validation (adapted from Kane, Crooks, & Cohen 1999).
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