Sentence examples for approach using human from inspiring English sources

A Complementarity Determining Region (CDR) grafting approach using human germline IgG frameworks was used to produce a panel of humanised variants of 1A3B-7, from which a single candidate molecule with retained binding specificity was identified.

To investigate genome-wide binding of Drosha, we employed a ChIP-on-chip approach using human 5.1.1 ENCODE array.

Recently, a new approach using human monoclonal IgE has been used to describe an IgE epitope to Bet v 1 [ 6].

An approach using human genes that complement IR sensitivity of mutant hamster cells was used to identify mammalian genes that are essential for HR.

Thus, we now provide a single therapeutic approach using human cells that promotes behavioral recovery, rescues both dopaminergic and parvalbumin-expressing neurons and increases expression of synaptophysin in an experimental model of PD.

By employing a complementary approach using human and mouse cortical neurons, we provide the first evidence that spatacsin has a major impact on neurite plasticity through maintaining cytoskeleton stability and SV transport.

A third approach used human cell extracts to drive SV40 DNA replication of plasmid templates with (CAGCTG 79 repeats.

Cell therapy approaches using human hepatocytes or stem cell-derived hepatocyte-like cells may be a therapeutic option out of this dilemma.

In fact, different proteomic approaches using human cell lines aimed at isolating factors enriched at or in the proximity of replication forks have recently revealed the presence of the recombination proteins Mre11 and Rad50 41, 41.

Several conclusions can be drawn from these studies, the most apparent being that significant differences can exist at the molecular and cellular level in humans and rodents, and that rodent-based studies may benefit from complementary approaches using human cells of the appropriate type.

Invasive experimental approaches using humans are not possible for obvious ethical reasons.